Increased basophils (> 0.1 x 109/l) seen in:
Basophilia does not characteristically occur in secondary polycythaemia.
Note that excessive basophilia in chronic myeloid leukaemia may indicate the transformation into an accelerated or 'blastic' phase.
Transient basophilia is a reactive response, especially to an acute viral illness. Persistent basophilia on serial blood counts for longer than 8 weeks suggests an underlying malignancy or myeloproliferative disease.
Reference
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