chloroquine-resistant falciparum malaria is now widespread (effectively universal) P. falciparum has also developed resistance to a variety of other agents in certain areas
Chloroquine remains effective against P. ovale and P. malariae
Chloroquine-resistant P. vivax is found in the Indonesian archipelago, the Malay Peninsula, including Myanmar, and eastward to Southern Vietnam and may have spread further.
P. vivax with reduced susceptibility to primaquine is found in South-East Asia and Oceania and higher doses of primaquine are required to achieve radical cure of this parasite from those areas. A higher dose may also be required for P. vivax from India, Pakistan, Afghanistan and South America
Reference
UK Health Security Agency. Malaria prevention guidelines for travellers from the UK (online). Last updated April 2025
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